Protein Structure Determination, Fall 2016

Meets Mon/Thurs 10-11:50 in J-Rowl 2C13

Syllabus for 2016


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√ Term Project (2016) 

Lectures

∅√     What     When
 
------- Second half: X-ray crystallography -------
 
Xray Lecture 1    Overview. Crystals. Symmetry.    PDF    Oct 6, 2016
Xray Lecture 2    The scattering of X-rays by electrons.. PDF    Oct 24, 2016
Xray Lecture 3    Bragg’s law. Diffraction. PDF    Oct 27, 2016
Xray Lecture 4    The Reciprocal lattice. B-factors. PDF    Oct 31, 2016 HW1 due
Xray Lecture 5    Phasing. Isomorphous replacement. PDF    Nov 3, 2016
Xray Lecture 5    Phasing. Isomorphous replacement (cont'd). PDF    Nov 7, 2016
Xray Lecture 6    Anomalous scattering. PDF    Nov 10, 2016
Xray Lecture 8    Error sources. CCP4 lab. PDF    Nov 14, 2016 HW2 due
Xray Lecture 9    Molecular replacement. Phenix lab PDF    Nov 17, 2016
Xray Lecture 10    Manual refinement. Coot lab PDF    Nov 21, 2016
Xray Lecture 11    Automated Refinement. PDF    Nov 28, 2016
Xray Lecture 12    Laue photography and MicroED. PDF    Dec 1, 2016 HW3 due
    Review session.     Dec 5, 2016
    Student presentations.     Dec 8, 2016
 
-------- Final exam (Xray only) ---------
Dec 15, 2016 11:30 - 2:30 Lally 102
Go to Prof Wang's course page
Aug 27 - Oct 11

Links etc

 Syllabus   Unix stuff  Download Jmol Download XrayView Download CCP4
 Movie 1   Movie 2   Bragg Planes (java)   Homework 4 
 Homework 5   Term Project   Get a PDB file   Homework 6   Homework X 
 short course 1   short course 2   MolProbity   Escher web sketch 
 Coot tutorial   Full Xray data set (716 Mb zip file) 
 Fobs map   Unrefined coordinates   Spacegroup images   Crystal math 
 COOT tutorial PDB file   COOT tutorial MTZ file 
 PDB for Phenix  MTZ for Phenix  SEQ for Phenix

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Last updated Fri Nov 11 18:30:44 EST 2016 W3C validation