Protein Structure Determination, Fall 2014

Meets Mon/Thurs 10-11:50 in J-Rowl 2C13

Syllabus for 2015


Upload homework files here

 Term Project (2013) 

Lectures

∅√     What     When
 
------- First half: X-ray crystallography -------
 
Xray Lecture 1    Overview. Crystals. Symmetry.    PDF    Aug 31, 2015
Xray Lecture 2    The scattering of X-rays by electrons.. PDF    Sep 3, 2015
Xray Lecture 3    Bragg’s law. Diffraction. PDF    Sep 14, 2015
Xray Lecture 4    The Reciprocal lattice. B-factors. PDF    Sep 17, 2015 HW1 due
Xray Lecture 5    Phasing. Isomorphous replacement. PDF    Sep 21, 2015
Xray Lecture 6    Anomalous scattering. PDF    Sep 24, 2015
Xray Lecture 7    Molecular replacement. PDF    Sep 28, 2015
Xray Lecture 8    Model building. Manual refinement. PDF    Oct 1, 2015 HW2 due
Xray Lecture 9    Automated Refinement. PDF    Oct 5, 2015 Xray lab part 1 due
Xray Lecture 10    Model validation. PDF    Oct 8, 2015 Xray lab part 2 due
Xray Lecture 11    The Protein Data Bank. PDF    Oct 13, 2015 Xray lab part 3 due
Xray Lecture 12    Protein validation, comparison. PDF    Oct 15, 2015 Xray lab part 4 due
 
-------Midterm exam (Xray crystallography)-------
Oct 19, 2015
 
------- Second half: Solution NMR -------
 
Go to Prof Wang's course page
Oct 22 - Dec 11
 
-------- Presentations ---------
Dec 7, 2015
 
-------Final Exam (NMR only)-------
Dec 10, 2015

Links etc

 Syllabus   Unix stuff  Download Jmol Download XrayView Download CCP4
 Movie 1   Movie 2   Bragg Planes (java)   Homework 4 
 Homework 5   Term Project   Get a PDB file   Homework 6   Homework X 
 short course 1   short course 2   MolProbity   Escher web sketch 
 Full Xray data set (716 Mb zip file)   Subset Xray data (169Mb)   Molrep model   Molrep MTZ file 
 Fobs map   Unrefined coordinates   Spacegroup images   Crystal math 
 COOT tutorial PDB file   COOT tutorial MTZ file 

Back to Courses page

Back to my home page


email me


Last updated Wed Nov 6 14:26:16 EST 2013 W3C validation