Protein Structure Determination, Fall 2013


Syllabus for 2013


Upload homework files here

 Term Project (2013) 

Lectures

∅√     What     When
 
------- First half: Solution NMR -------
 
Go to Prof Wang's course page
Aug 27 - Oct 11
 
-------MIDTERM (NMR)-------
Oct 10, 2012
 
------- Second half: X-ray crystallography -------
 
Xray Lecture 1    Overview. Crystals. Symmetry.    PDF    Oct 15, 2013
Xray Lecture 2    The scattering of X-rays by electrons.. PDF    Oct 17, 2013
Xray Lecture 3    Bragg’s law. Diffraction. PDF    Oct 21, 2013
Xray Lecture 4    The Reciprocal lattice. B-factors. PDF    Oct 24, 2013 HW1 due
Xray Lecture 5    Phasing. Isomorphous replacement. PDF    Oct 28, 2013
Xray Lecture 6    Anomalous scattering. PDF    Oct 31, 2013
Xray Lecture 7    Molecular replacement. PDF    Nov 4, 2013
Xray Lecture 8    Model building. Manual refinement. PDF    Nov 7, 2013 HW2 due
Xray Lecture 9    Automated Refinement. PDF    Nov 11, 2013 Xray lab part 1 due
Xray Lecture 10    Model validation. PDF    Nov 14, 2013 Xray lab part 2 due
Xray Lecture 11    The Protein Data Bank. PDF    Nov 18, 2013 Xray lab part 3 due
Xray Lecture 12    Exploring X-ray structures. PDF    Nov 21, 2013 Xray lab part 4 due
Xray Lecture 12    Exploring X-ray structures. PDF    Nov 25, 2013 HW3 due
 
-------- no class ---------
Dec 2, 2012
 
-------- Presentations ---------
Dec 5, 2012
 
-------Final Exam (Xray only)-------
Dec 13, 3-5pm 2C13

Links etc

 Syllabus   Unix stuff  Download Jmol Download XrayView Download CCP4
 Movie 1   Movie 2   Bragg Planes (java)   Homework 4 
 Homework 5   Term Project   Get a PDB file   Homework 6   Homework X 
 short course 1   short course 2   MolProbity   Escher web sketch 
 Full Xray data set (716 Mb zip file)   Subset Xray data (169Mb)   Molrep model   Molrep MTZ file 
 Fobs map   Unrefined coordinates   Spacegroup images   Crystal math 
 COOT tutorial PDB file   COOT tutorial MTZ file 

Back to Courses page

Back to my home page


email me


Last updated Wed Nov 6 14:26:16 EST 2013 W3C validation