Protein Structure Determination, Fall 2014

Meets Mon/Thurs 10-11:50 in J-Rowl 2C13

Syllabus for 2014


Upload homework files here

 Term Project (2013) 

Lectures

∅√     What     When
 
------- First half: X-ray crystallography -------
 
Xray Lecture 1    Overview. Crystals. Symmetry.    PDF    Aug 25, 2014
Xray Lecture 2    The scattering of X-rays by electrons.. PDF    Aug 28, 2014
Xray Lecture 3    Bragg’s law. Diffraction. PDF    sep 4, 2014
Xray Lecture 4    The Reciprocal lattice. B-factors. PDF    Sep 8, 2014 HW1 due
Xray Lecture 5    Phasing. Isomorphous replacement. PDF    Sep 11, 2014
Xray Lecture 6    Anomalous scattering. PDF    Sep 15, 2014
Xray Lecture 7    Molecular replacement. PDF    Sep 18, 2014
Xray Lecture 8    Model building. Manual refinement. PDF    Sep 22, 2014 HW2 due
Xray Lecture 9    Automated Refinement. PDF    Sep 25, 2014 Xray lab part 1 due
Xray Lecture 10    Model validation. PDF    Sep 29, 2014 Xray lab part 2 due
Xray Lecture 11    The Protein Data Bank. PDF    Oct 2, 2014 Xray lab part 3 due
Xray Lecture 12    Protein validation, comparison. PDF    Oct 6, 2014 Xray lab part 4 due
Xray Lecture 13    Special topic. PDF    Oct 9, 2014 HW3 due
 
-------- review session (tuesday!)---------
Oct 14, 2014
 
-------Midterm exam (Xray crystallography)-------
Oct 16, 2014
 
------- Second half: Solution NMR -------
 
Go to Prof Wang's course page
Aug 27 - Oct 11
 
-------- Presentations ---------
Dec 5, 2012
 
-------Final Exam (NMR only)-------
Oct 10, 2012

Links etc

 Syllabus   Unix stuff  Download Jmol Download XrayView Download CCP4
 Movie 1   Movie 2   Bragg Planes (java)   Homework 4 
 Homework 5   Term Project   Get a PDB file   Homework 6   Homework X 
 short course 1   short course 2   MolProbity   Escher web sketch 
 Full Xray data set (716 Mb zip file)   Subset Xray data (169Mb)   Molrep model   Molrep MTZ file 
 Fobs map   Unrefined coordinates   Spacegroup images   Crystal math 
 COOT tutorial PDB file   COOT tutorial MTZ file 

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Last updated Wed Nov 6 14:26:16 EST 2013 W3C validation