Protein Structure Determination, Fall 2011


Syllabus for 2011


Upload homework files here

HW6 is due Dec 5

 Possible Final Exam Questions 

Lectures

    What     When
 
------- First half: Solution NMR -------
 
 
Go to Prof Wang's course page
Aug 30 - Oct 18
 
-------MIDTERM (NMR)-------
Oct 14, 2011
 
------- Second half: X-ray crystallography -------
 
Xray Lecture 1    Overview. Crystals.    PDF    Oct 11, 2011
Xray Lecture 2    The scattering of X-rays by electrons.. PDF    Oct 20, 2011
Xray Lecture 3    Bragg's law. The Fourier transform. PDF    Oct 24, 2011
Xray Lecture 4    Diffraction. The Reciprocal lattice. PDF    Oct 27, 2011
Xray Lecture 5    Symmetry. PDF    Oct 31, 2011
Xray Lecture 6    Atomic scattering factors. The Patterson function. PDF    Nov 3, 2011 HW4 due
Xray Lecture 7    Solving the phase problem. MIR & SIR. PDF    Nov 7, 2011
Xray Lecture 8    Anomalous scattering. MAD & SAD. PDF    Nov 10, 2011
Xray Lecture 9    Molecular replacement. PDF    Nov 14, 2011
Xray Lecture 10    Refinement. PDF    Nov 17, 2011 HW5 due
Xray Lecture 11    CCP4 lab. PDF    Nov 21, 2011
Xray Lecture 12    Coot lab. PDF    Nov 28, 2011
Xray Lecture 12    Validation. Exploring X-ray structures. PDF    Dec 1, 2011 HW6 due
 
-------- Presentations ---------
Dec 5, 2011
 
-------- Presentations ---------
Dec 8, 2011
 
-------Final Exam (Xray only)-------
Dec 19, 2011 1-3pm in 2C13

Links etc

 Syllabus   Unix stuff  Download Jmol Download XrayView Download CCP4
 Movie 1   Movie 2   Bragg Planes (java)   Homework 4 
 Homework 5   Term Project   Get a PDB file   Homework 6   Homework X 
 short course 1   short course 2   MolProbity   Escher web sketch 
 Full Xray data set (716 Mb)   Xray data (subset 169Mb)   Molrep model   Molrep MTZ file 
 Fobs map   Unrefined coordinates 

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Last updated Wed Dec 7 15:14:07 EST 2011 W3C validation