Professor Michael Zuker and Chip Lawrence
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Mandelbrot Set
NOS Molecule
i-sites plot
i-sites graph
Folding of RNA Molecule
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Applications
-- Home >> Applications >> Bayesian >> I-sites >> RNA & DNA Folding >> Sfold

Serving the Scientific Community

The RPI-Wadsworth Bioinformatics Center offers some of its reasearch software to the entire scientific and medical community nation wide and world wide through its bioinformatics web server. In addition, other useful, more traditional applications programmed by RPI students are offered. The web server is currently a cluster of 36 dual processor Intel based computers running Red Hat Linux. The current equipment was donated by IBM in an SUR (Shared University Research) grant to Michael Zuker, PI.

Applications

Bayesian - algorithms for macromolecular structure analysis and inference technology for molecular and structural biology

I-sites
- a new method for predicting the local structure of a protein from its amino acid sequence

RNA & DNA Folding
- algorithms and thermodynamics for nucleic acid secondary structure, hybridization and melting predictions.

Nucleic Acid Hybridization & Melting

Sfold - statistical algorithms and tools for RNA secondary structure and target accessibility prediction, and rational design of RNA-targeting nucleic acids.

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